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evinacumab

Pronunciation: E vin AK ue mab

Brand: Evkeeza

What is the most important information I should know about evinacumab?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What is evinacumab?

Evinacumab is used with other medications to lower cholesterol in adults and children at least 12 years old who have an inherited type of high cholesterol.

Evinacumab is not for use in treating high cholesterol that is caused by diet or other factors.

Evinacumab may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before receiving evinacumab?

You should not be treated with evinacumab if you are allergic to it.

You may need to have a negative pregnancy test before starting this treatment.

Evinacumab may harm an unborn baby. Use effective birth control to prevent pregnancy while using evinacumab, and for at least 5 months after your last dose. Tell your doctor if you become pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Evinacumab is not approved for use by anyone younger than 12 years old.

How is evinacumab given?

Evinacumab is given as an infusion into a vein, usually once per month. A healthcare provider will give you this injection.

This medicine must be given slowly, and the infusion can take about 60 minutes to complete.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your evinacumab injection.

What happens if I overdose?

Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while receiving evinacumab?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of evinacumab?

Get emergency medical help if you have signs of an allergic reaction: hives, rash, itching; feeling light-headed; wheezing, difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects may occur during the injection. Tell your caregiver if you feel nauseated, itchy, feverish, or have a stuffy nose or muscle weakness.

Your evinacumab treatments may be delayed or permanently discontinued if you have certain side effects.

Common side effects may include:

  • cold or flu symptoms such as fever, chills, body aches, stuffy nose, sneezing, sore throat;
  • dizziness;
  • pain in your arms or legs;
  • nausea; or
  • lack of energy.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect evinacumab?

Other drugs may affect evinacumab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Your pharmacist can provide more information about evinacumab.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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