Our Health Library information does not replace the advice of a doctor. Please be advised that this information is made available to assist our patients to learn more about their health. Our providers may not see and/or treat all topics found herein.

magnesium sulfate, potassium chloride, and sodium sulfate

Pronunciation: mag NEE zee um SUL fate, poe TASS ee um KLOR ide, and SOE dee um SUL fate

Brand: Sutab

What is the most important information I should know about this medicine?

This medicine can cause severe dehydration, which can lead to a serious electrolyte imbalance, seizures, or kidney failure.

Call your doctor if you are sick with vomiting and cannot drink enough water for your bowel prep, or if you have a headache, dizziness, or decreased urination.

What is magnesium sulfate, potassium chloride, and sodium sulfate (Sutab)?

Magnesium, potassium, and sodium are electrolyte minerals that occur naturally in body fluids.

Magnesium, potassium, and sodium sulfates (Sutab) is a combination medicine that causes diarrhea for the purpose of cleaning your colon before a colonoscopy. Cleaning the colon (bowel prep) allows the inside of your colon to be seen more clearly on the colonoscopy.

Magnesium, potassium, and sodium sulfates may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking this medicine?

You should not use Sutab if you are allergic to magnesium sulfate, potassium sulfate, or sodium sulfate, or if you have:

  • a bowel obstruction, colitis or toxic megacolon;
  • a dilated intestine;
  • a perforation (a hole or tear) of your intestines; or
  • slow digestion.

Tell your doctor if you have ever had:

  • heart problems, including long QT syndrome;
  • a stomach or intestinal disorder such as ulcerative colitis;
  • gastroesophageal reflux disease (GERD);
  • trouble swallowing;
  • an electrolyte imbalance (such as low levels of potassium, magnesium, or sodium in your blood);
  • a seizure;
  • kidney disease; or
  • if you are in withdrawal from alcoholism or addiction to Valium-like sedatives (benzodiazepines).

Tell your doctor if you are pregnant or breastfeeding.

This medicine is not approved for use by anyone younger than 18 years old.

How should I take this medicine?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Carefully follow all instructions about what to eat or drink in the days before your bowel prep, and when to stop eating solid foods.

Sutab is usually taken in 2 doses. Each dose consists of 12 tablets taken at one time, with 16 ounces of water. Take the first dose the evening before your colonoscopy and take the second dose the morning of your colonoscopy.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

You will need to drink extra water once you start your bowel prep. Drink only clear liquids and avoid alcohol, milk, or any drink that is red or purple.

You should be finished with all doses at least 2 hours before your colonoscopy.

This medicine can cause severe dehydration, which can lead to a serious electrolyte imbalance, seizures, or kidney failure. Call your doctor if you are sick with vomiting and cannot drink enough water for your bowel prep, or if you have a headache, dizziness, or decreased urination.

Store at room temperature.

What happens if I miss a dose?

Call your doctor if you cannot drink the entire amount of medicine and liquids as instructed in time for your colonoscopy.

What happens if I overdose?

An overdose is unlikely to occur if you take this medicine exactly as directed.

What should I avoid while taking this medicine?

Do not take other laxatives during your bowel prep.

What are the possible side effects of this medicine?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor right away if you have:

  • trouble drinking liquids;
  • nausea, painful bloating, stomach cramps, vomiting;
  • little or no urination;
  • a seizure;
  • rectal bleeding; or
  • signs of an electrolyte imbalance --increased thirst or urination, confusion, slurred speech, dizziness, weakness, feeling jittery or unsteady, constipation, muscle pain or weakness, leg cramps, numbness or tingling, irregular heartbeats, fluttering in your chest.

Common side effects may include:

  • stomach pain or discomfort;
  • nausea, vomiting; or
  • mild bloating.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Sutab?

Sutab can make it harder for your body to absorb other medicines you take by mouth (orally). Do not take any oral medicine within 1 hour before you start taking Sutab.

If you take any of the following medicines, take your Sutab dose 6 hours before or 2 hours after you take the other medicine:

  • chlorpromazine;
  • digoxin;
  • iron; or
  • certain antibiotics --ciprofloxacin, delafloxacin, gemifloxacin, levofloxacin, moxifloxacin, ofloxacin, penicillamine, tetracycline.

Tell your doctor about all your other medicines, especially:

  • heart or blood pressure medication;
  • a diuretic or "water pill";
  • medicine to treat a kidney problem;
  • medicine for depression or mental illness;
  • seizure medication; or
  • NSAIDs (nonsteroidal anti-inflammatory drugs) --aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

This list is not complete. Other drugs may affect Sutab, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your doctor or pharmacist can provide more information about magnesium, potassium, and sodium sulfates.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2021 Cerner Multum, Inc. Version: 1.01. Revision date: 12/11/2020.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by End-User License Agreement, which can be accessed by clicking on this link.