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glycerin, petrolatum, phenylephrine, and pramoxine topical

Pronunciation: GLIS er in PET roe LAY tum FEN il EF rin pra MOX een TOP i kal

Brand: Preparation H Maximum Strength, Preparation H Multi-Symptom

What is the most important information I should know about this medicine?

Ask a doctor or pharmacist before using this medicine if you are using a medication to treat asthma, COPD, or depression.

What is glycerin, petrolatum, phenylephrine, and pramoxine topical?

Glycerin, petrolatum, phenylephrine, and pramoxine topical is a combination medicine used to relieve pain, soreness, burning, itching, and swelling caused by hemorrhoids.

This medicine may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using this medicine?

Tell your doctor if you have ever had:

  • heart disease;
  • high blood pressure;
  • enlarged prostate or urination problems;
  • diabetes; or
  • a thyroid disorder.

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

Do not give this medicine to a child younger than 12 years old without medical advice.

How should I use this medicine?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Do not take by mouth. This medicine is for use only on the skin around your rectum. Rinse with water if this medicine gets in your eyes or mouth.

You may use this medicine up to 4 times daily, especially after a bowel movement.

Apply the medicine to the skin around the outside of your rectum only. Do not get this medicine inside your rectum.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Call your doctor if your symptoms do not improve after 7 days, or if they get worse.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Since this medicine is used when needed, you may not be on a dosing schedule. Skip any missed dose if it's almost time for your next dose. Do not use more than 4 times per day.

What happens if I overdose?

An overdose of this medicine is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

What should I avoid while using this medicine?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of this medicine?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

  • severe irritation inside or around your rectum;
  • rectal pain, redness, swelling; or
  • any new or worsening hemorrhoid symptoms.

Less serious side effects are more likely, and you may have none at all.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect this medicine?

Ask a doctor or pharmacist before using glycerin, petrolatum, phenylephrine, and pramoxine topical with any other medications, especially:

  • an antidepressant;
  • a bronchodilator medicine for asthma or COPD; or
  • ergot medicine--dihydroergotamine, ergotamine, ergonovine, methylergonovine.

This list is not complete. Other drugs may affect glycerin, petrolatum, phenylephrine, and pramoxine topical, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your pharmacist can provide more information about this medicine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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