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hydrochlorothiazide and bisoprolol

Pronunciation: HYE droe klor oh THYE a zide and bi SOE proe lol

Brand: Ziac

Bisoprolol-Hydrochlorothiazide

slide 1 of 23, Bisoprolol-Hydrochlorothiazide,

2.5 mg-6.25 mg, round, peach, imprinted with E 701

Image of Bisoprolol-Hydrochlorothiazide
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Bisoprolol-Hydrochlorothiazide

slide 2 of 23, Bisoprolol-Hydrochlorothiazide,

5 mg-6.25 mg, round, red, imprinted with E 704

Image of Bisoprolol-Hydrochlorothiazide
slide 2 of 23
    

Bisoprolol-Hydrochlorothiazide

slide 3 of 23, Bisoprolol-Hydrochlorothiazide,

10 mg-6.25 mg, round, white, imprinted with E 707

Image of Bisoprolol-Hydrochlorothiazide
slide 3 of 23
    

Bisoprolol-Hydrochlorothiazide

slide 4 of 23, Bisoprolol-Hydrochlorothiazide,

2.5 mg-6.25 mg, round, orange, imprinted with 501, M

Image of Bisoprolol-Hydrochlorothiazide
slide 4 of 23
    

Bisoprolol-Hydrochlorothiazide

slide 5 of 23, Bisoprolol-Hydrochlorothiazide,

5 mg-6.25 mg, round, blue, imprinted with 503, M

Image of Bisoprolol-Hydrochlorothiazide
slide 5 of 23
    

Bisoprolol-Hydrochlorothiazide

slide 6 of 23, Bisoprolol-Hydrochlorothiazide,

10 mg-6.25 mg, round, white, imprinted with 505, M

Image of Bisoprolol-Hydrochlorothiazide
slide 6 of 23
    

Bisoprolol-Hydrochlorothiazide

slide 7 of 23, Bisoprolol-Hydrochlorothiazide,

2.5 mg-6.25 mg, round, yellow, imprinted with UL

Image of Bisoprolol-Hydrochlorothiazide
slide 7 of 23
    

Bisoprolol-Hydrochlorothiazide

slide 8 of 23, Bisoprolol-Hydrochlorothiazide,

5 mg-6.25 mg, round, pink, imprinted with UL, ll

Image of Bisoprolol-Hydrochlorothiazide
slide 8 of 23
    

Bisoprolol-Hydrochlorothiazide

slide 9 of 23, Bisoprolol-Hydrochlorothiazide,

10 mg-6.25 mg, round, white, imprinted with UL, lll

Image of Bisoprolol-Hydrochlorothiazide
slide 9 of 23
    

Ziac

slide 10 of 23, Ziac,

2.5 mg-6.25 mg, round, yellow, imprinted with b, 47

Image of Ziac
slide 10 of 23
    

Bisoprolol-Hydrochlorothiazide

slide 11 of 23, Bisoprolol-Hydrochlorothiazide,

10 mg-6.25 mg, oblong, white, imprinted with 652, R

Image of Bisoprolol-Hydrochlorothiazide
slide 11 of 23
    

Bisoprolol-Hydrochlorothiazide

slide 12 of 23, Bisoprolol-Hydrochlorothiazide,

10 mg-6.25 mg, round, white, imprinted with 843, WATSON

Image of Bisoprolol-Hydrochlorothiazide
slide 12 of 23
    

Bisoprolol-Hydrochlorothiazide

slide 13 of 23, Bisoprolol-Hydrochlorothiazide,

2.5 mg-6.25 mg, round, yellow, imprinted with 841, WATSON

Image of Bisoprolol-Hydrochlorothiazide
slide 13 of 23
    

Bisoprolol-Hydrochlorothiazide

slide 14 of 23, Bisoprolol-Hydrochlorothiazide,

5 mg-6.25 mg, round, pink, imprinted with 842, WATSON

Image of Bisoprolol-Hydrochlorothiazide
slide 14 of 23
    

Bisoprolol-Hydrochlorothiazide

slide 15 of 23, Bisoprolol-Hydrochlorothiazide,

10 mg-6.25 mg, round, white, imprinted with 505, M

Image of Bisoprolol-Hydrochlorothiazide
slide 15 of 23
    

Bisoprolol-Hydrochlorothiazide

slide 16 of 23, Bisoprolol-Hydrochlorothiazide,

2.5 mg-6.25 mg, round, orange, imprinted with 501, M

Image of Bisoprolol-Hydrochlorothiazide
slide 16 of 23
    

Bisoprolol-Hydrochlorothiazide

slide 17 of 23, Bisoprolol-Hydrochlorothiazide,

5 mg-6.25 mg, round, blue, imprinted with 503, M

Image of Bisoprolol-Hydrochlorothiazide
slide 17 of 23
    

Ziac

slide 18 of 23, Ziac,

10 mg-6.25 mg, round, white, imprinted with b, 40

Image of Ziac
slide 18 of 23
    

Ziac

slide 19 of 23, Ziac,

10 mg-6.25 mg, round, white, imprinted with LL, B 14

Image of Ziac
slide 19 of 23
    

Ziac

slide 20 of 23, Ziac,

2.5 mg-6.25 mg, round, yellow, imprinted with b, 47

Image of Ziac
slide 20 of 23
    

Ziac

slide 21 of 23, Ziac,

2.5 mg-6.25 mg, round, yellow, imprinted with LL, B 12

Image of Ziac
slide 21 of 23
    

Ziac

slide 22 of 23, Ziac,

5 mg-6.25 mg, round, pink, imprinted with b, 50

Image of Ziac
slide 22 of 23
    

Ziac

slide 23 of 23, Ziac,

5 mg-6.25 mg, round, pink, imprinted with LL, B 13

Image of Ziac
slide 23 of 23
    

What is the most important information I should know about hydrochlorothiazide and bisoprolol?

You should not use this medicine if you are unable to urinate. You should not use hydrochlorothiazide and bisoprolol if you have a serious heart condition such as "sick sinus syndrome" or "AV block," severe heart failure, or slow heartbeats that have caused you to faint.

What is hydrochlorothiazide and bisoprolol?

Hydrochlorothiazide is a thiazide diuretic (water pill). Bisoprolol is a beta-blocker.

Hydrochlorothiazide and bisoprolol is a combination medicine used to treat high blood pressure (hypertension).

Hydrochlorothiazide and bisoprolol may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking hydrochlorothiazide and bisoprolol?

You should not use this medicine if you are allergic to hydrochlorothiazide or bisoprolol, or if you have:

  • severe or uncontrolled heart failure;
  • slow heartbeats that have caused you to faint;
  • a serious heart condition called "sick sinus syndrome" or "AV block" (2nd or 3rd degree);
  • an allergy to sulfa drugs; or
  • if you are unable to urinate.

Tell your doctor if you have ever had:

  • congestive heart failure;
  • asthma or other breathing disorder;
  • diabetes;
  • a thyroid disorder;
  • glaucoma;
  • peripheral vascular disease such as Raynaud's syndrome;
  • kidney disease;
  • liver disease (or cirrhosis);
  • lupus;
  • gout; or
  • an allergy to sulfa drugs or penicillin.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

You should not breastfeed while using this medicine.

This medicine is not approved for use by anyone younger than 18 years old.

How should I take hydrochlorothiazide and bisoprolol?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking hydrochlorothiazide and bisoprolol. This can lead to very low blood pressure, a serious electrolyte imbalance, or kidney failure.

Your blood pressure will need to be checked often. Your blood and urine may both be tested if you have been vomiting or are dehydrated.

If you are diabetic, check your blood sugar carefully. Taking bisoprolol may make it harder for you to tell when you have low blood sugar. Your insulin or diabetes medication needs may change while you are taking hydrochlorothiazide and bisoprolol. Do not change your medication dose or schedule without your doctor's advice.

If you need surgery or medical tests, tell the doctor you currently use this medicine. You may need to stop for a short time.

Do not skip doses or stop using hydrochlorothiazide and bisoprolol suddenly. Stopping suddenly may make your condition worse. Follow your doctor's instructions about tapering your dose.

Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

Store at room temperature, away from heat and moisture. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include confusion, leg cramps, numbness and tingling, slow heartbeats or fainting.

What should I avoid while taking hydrochlorothiazide and bisoprolol?

Avoid drinking alcohol. It may increase your blood levels of bisoprolol.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Hydrochlorothiazide may increase your risk of skin cancer. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Your doctor may want you to have skin examinations on a regular basis.

What are the possible side effects of hydrochlorothiazide and bisoprolol?

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Call your doctor at once if you have:

  • chest pain;
  • fast, slow, or uneven heartbeats;
  • a light-headed feeling, like you might pass out;
  • blurred vision, tunnel vision, eye pain, or seeing halos around lights;
  • shortness of breath (even with mild exertion), swelling, rapid weight gain;
  • liver problems --nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • signs of an electrolyte imbalance --increased thirst or urination, constipation, muscle pain or weakness, leg cramps, numbness or tingling, feeling jittery, irregular heartbeats, fluttering in your chest, or a choking feeling;
  • low blood sugar --headache, hunger, sweating, irritability, dizziness, fast heart rate, and feeling anxious or shaky.

Common side effects may include:

  • dizziness;
  • feeling weak or tired;
  • diarrhea, nausea, indigestion;
  • headache; or
  • cough.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect hydrochlorothiazide and bisoprolol?

Tell your doctor about all your other medicines, especially:

  • colestipol or cholestyramine;
  • insulin or oral diabetes medicine;
  • lithium;
  • sedatives or narcotic medicine;
  • heart or blood pressure medicine --clonidine, digoxin, diltiazem, disopyramide, reserpine, verapamil, and others;
  • NSAIDs (nonsteroidal anti-inflammatory drugs) --aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others; or
  • steroid medicine --prednisone and others.

This list is not complete. Other drugs may affect hydrochlorothiazide and bisoprolol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your pharmacist can provide more information about hydrochlorothiazide and bisoprolol.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2021 Cerner Multum, Inc. Version: 9.01. Revision date: 3/30/2021.

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